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Role of the RNA polymerase trigger loop in nucleotidyl transfer, transcript cleavage, and transcriptional pausing
The trigger loop (TL) is a polymorphous component of RNA polymerase (RNAP) that makes direct substrate contacts and promotes nucleotide addition when folded into an α-helical hairpin (trigger helices; TH). However, the roles of the TL/TH in transcript cleavage, catalysis, substrate selectivity, and...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2904963/ https://ncbi.nlm.nih.gov/pubmed/19966797 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1732 |
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