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The Construction and Use of Log-Odds Substitution Scores for Multiple Sequence Alignment

Most pairwise and multiple sequence alignment programs seek alignments with optimal scores. Central to defining such scores is selecting a set of substitution scores for aligned amino acids or nucleotides. For local pairwise alignment, substitution scores are implicitly of log-odds form. We now exte...

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Bibliografski detalji
Glavni autori: Altschul, Stephen F., Wootton, John C., Zaslavsky, Elena, Yu, Yi-Kuo
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904766/
https://ncbi.nlm.nih.gov/pubmed/20657661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000852
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