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The Construction and Use of Log-Odds Substitution Scores for Multiple Sequence Alignment
Most pairwise and multiple sequence alignment programs seek alignments with optimal scores. Central to defining such scores is selecting a set of substitution scores for aligned amino acids or nucleotides. For local pairwise alignment, substitution scores are implicitly of log-odds form. We now exte...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2904766/ https://ncbi.nlm.nih.gov/pubmed/20657661 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000852 |
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