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The compositional adjustment of amino acid substitution matrices
Amino acid substitution matrices are central to protein-comparison methods. In most commonly used matrices, the substitution scores take a log-odds form, involving the ratio of “target” to “background” frequencies derived from large, carefully curated sets of protein alignments. However, such matric...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC307629/ https://ncbi.nlm.nih.gov/pubmed/14663142 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2533904100 |
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