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The compositional adjustment of amino acid substitution matrices

Amino acid substitution matrices are central to protein-comparison methods. In most commonly used matrices, the substitution scores take a log-odds form, involving the ratio of “target” to “background” frequencies derived from large, carefully curated sets of protein alignments. However, such matric...

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Détails bibliographiques
Auteurs principaux: Yu, Yi-Kuo, Wootton, John C., Altschul, Stephen F.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2003
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC307629/
https://ncbi.nlm.nih.gov/pubmed/14663142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2533904100
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