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Protein Database Searches Using Compositionally Adjusted Substitution Matrices

Almost all protein database search methods use amino acid substitution matrices for scoring, optimizing, and assessing the statistical significance of sequence alignments. Much care and effort has therefore gone into constructing substitution matrices, and the quality of search results can depend st...

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Detalhes bibliográficos
Main Authors: Altschul, Stephen F., Wootton, John C., Gertz, E. Michael, Agarwala, Richa, Morgulis, Aleksandr, Schäffer, Alejandro A., Yu, Yi-Kuo
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1343503/
https://ncbi.nlm.nih.gov/pubmed/16218944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1742-4658.2005.04945.x
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