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Retrieval accuracy, statistical significance and compositional similarity in protein sequence database searches

Protein sequence database search programs may be evaluated both for their retrieval accuracy—the ability to separate meaningful from chance similarities—and for the accuracy of their statistical assessments of reported alignments. However, methods for improving statistical accuracy can degrade retri...

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Detalhes bibliográficos
Main Authors: Yu, Yi-Kuo, Gertz, E. Michael, Agarwala, Richa, Schäffer, Alejandro A., Altschul, Stephen F.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635310/
https://ncbi.nlm.nih.gov/pubmed/17068079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl731
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