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Two Origins for the Gene Encoding α-Isopropylmalate Synthase in Fungi
BACKGROUND: The biosynthesis of leucine is a biochemical pathway common to prokaryotes, plants and fungi, but absent from humans and animals. The pathway is a proposed target for antimicrobial therapy. METHODOLOGY/PRINCIPAL FINDINGS: Here we identified the leuA gene encoding α-isopropylmalate syntha...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2010
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2904702/ https://ncbi.nlm.nih.gov/pubmed/20657649 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011605 |
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