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Cation induced differential effect on structural and functional properties of Mycobacterium tuberculosis α-Isopropylmalate synthase
BACKGROUND: α-isopropylmalate synthase (MtαIPMS), an enzyme that catalyzes the first committed step of the leucine biosynthetic pathway of Mycobacterium tuberculosis is a potential drug target for the anti-tuberculosis drugs. Cations induce differential effect of activation and inhibition of MtαIPMS...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1919377/ https://ncbi.nlm.nih.gov/pubmed/17577419 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6807-7-39 |
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