Diversification of Paralogous α-Isopropylmalate Synthases by Modulation of Feedback Control and Hetero-Oligomerization in Saccharomyces cerevisiae

Production of α-isopropylmalate (α-IPM) is critical for leucine biosynthesis and for the global control of metabolism. The budding yeast Saccharomyces cerevisiae has two paralogous genes, LEU4 and LEU9, that encode α-IPM synthase (α-IPMS) isozymes. Little is known about the biochemical differences b...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Eukaryot Cell
Main Authors: López, Geovani, Quezada, Héctor, Duhne, Mariana, González, James, Lezama, Mijail, El-Hafidi, Mohammed, Colón, Maritrini, Martínez de la Escalera, Ximena, Flores-Villegas, Mirelle Citlali, Scazzocchio, Claudio, DeLuna, Alexander, González, Alicia
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4452578/
https://ncbi.nlm.nih.gov/pubmed/25841022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00033-15
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados