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Self-association mediated by the Ras association 1 domain of AF6 activates the oncogenic potential of MLL-AF6
MLL is a common target for chromosomal translocations associated with acute leukemia resulting in its fusion with a large variety of nuclear or cytoplasmic proteins that may activate its oncogenic properties by distinct but poorly understood mechanisms. The MLL-AF6 fusion gene represents the most co...
Gorde:
| Egile Nagusiak: | , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
American Society of Hematology
2010
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2904581/ https://ncbi.nlm.nih.gov/pubmed/20395419 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-09-243386 |
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