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Therapeutic targeting of MLL

Treatment of hematologic malignancies is evolving from a uniform approach to targeted therapies directed at the underlying molecular abnormalities of disease. The mixed lineage leukemia (MLL) proto-oncogene is a recurrent site of genetic rearrangements in acute leukemias; and since its discovery in...

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Bibliografski detalji
Glavni autori: Liedtke, Michaela, Cleary, Michael L.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2699228/
https://ncbi.nlm.nih.gov/pubmed/19289854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-12-197061
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