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Control of Volume-Sensitive Chloride Channel Inactivation by the Coupled Action of Intracellular Chloride and Extracellular Protons

The volume-sensitive chloride current (I(ClVol)) exhibit a time-dependent decay presumably due to channel inactivation. In this work, we studied the effects of Cl(-) and H(+) ions on I(ClVol) decay recorded in HEK-293 and HL-60 cells using the whole-cell patch clamp technique. Under control conditio...

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Detalhes bibliográficos
Main Authors: Hernández-Carballo, Carmen Y., De Santiago-Castillo, José A., Rosales-Saavedra, Teresa, Pérez-Cornejo, Patricia, Arreola, Jorge
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904426/
https://ncbi.nlm.nih.gov/pubmed/20454973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-010-0842-0
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