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Conformation-dependent regulation of inward rectifier chloride channel gating by extracellular protons

We have investigated the gating properties of the inward rectifier chloride channel (Cl(ir)) from mouse parotid acinar cells by external protons ([Formula: see text]) using the whole-cell patch-clamp technique. Increasing the pH(o) from 7.4 to 8.0 decreased the magnitude of Cl(ir) current by shiftin...

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Hlavní autoři: Arreola, Jorge, Begenisich, Ted, Melvin, James E
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2002
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2290315/
https://ncbi.nlm.nih.gov/pubmed/12015423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2002.016485
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