Lanean...

Computational Design of Second-Site Suppressor Mutations at Protein-Protein Interfaces

The importance of a protein-protein interaction to a signaling pathway can be established by showing that amino acid mutations that weaken the interaction disrupt signaling, and that additional mutations that rescue the interaction recover signaling. Identifying rescue mutations, often referred to a...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Sammond, Deanne W., Eletr, Ziad M., Purbeck, Carrie, Kuhlman, Brian
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903445/
https://ncbi.nlm.nih.gov/pubmed/19899154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.22631
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!