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Computational Design of Affinity and Specificity at Protein-Protein Interfaces

The computer-based design of protein-protein interactions is a rigorous test of our understanding of molecular recognition and an attractive approach for creating novel tools for cell and molecular research. Considerable attention has been placed on redesigning the affinity and specificity of natura...

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Detalhes bibliográficos
Main Authors: Karanicolas, John, Kuhlman, Brian
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2882636/
https://ncbi.nlm.nih.gov/pubmed/19646858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2009.07.005
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