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Anchored Design of Protein-Protein Interfaces

BACKGROUND: Few existing protein-protein interface design methods allow for extensive backbone rearrangements during the design process. There is also a dichotomy between redesign methods, which take advantage of the native interface, and de novo methods, which produce novel binders. METHODOLOGY: He...

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Detalhes bibliográficos
Main Authors: Lewis, Steven M., Kuhlman, Brian A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3117852/
https://ncbi.nlm.nih.gov/pubmed/21698112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020872
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