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Using Anchoring Motifs for the Computational Design of Protein-Protein Interactions
The computer-based design of protein-protein interactions is a challenging problem because large desolvation and entropic penalties must be overcome by the creation of favorable hydrophobic and polar contacts at the target interface. Indeed, many computationally designed interactions fail to form wh...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4112732/ https://ncbi.nlm.nih.gov/pubmed/24059499 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20130108 |
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