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Metal templated design of protein interfaces
Metal coordination is a key structural and functional component of a large fraction of proteins. Given this dual role we considered the possibility that metal coordination may have played a templating role in the early evolution of protein folds and complexes. We describe here a rational design appr...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2836610/ https://ncbi.nlm.nih.gov/pubmed/20080561 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0906852107 |
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