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Metal templated design of protein interfaces

Metal coordination is a key structural and functional component of a large fraction of proteins. Given this dual role we considered the possibility that metal coordination may have played a templating role in the early evolution of protein folds and complexes. We describe here a rational design appr...

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Detaylı Bibliyografya
Asıl Yazarlar: Salgado, Eric N., Ambroggio, Xavier I., Brodin, Jeffrey D., Lewis, Richard A., Kuhlman, Brian, Tezcan, F. Akif
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836610/
https://ncbi.nlm.nih.gov/pubmed/20080561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0906852107
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