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Metal-Templated Design of Chemically Switchable Protein Assemblies with High-Affinity Coordination Sites

To mimic a hypothetical pathway for protein evolution, we previously developed a design strategy (Metal-Templated Interface Redesign), in which a monomeric protein (cytochrome cb(562)) was tailored for metal-mediated self-assembly, followed by the re-design of the resulting oligomers for enhanced st...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Kakkis, Albert, Gagnon, Derek, Esselborn, Julian, Britt, R. David, Tezcan, F. Akif
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7983065/
https://ncbi.nlm.nih.gov/pubmed/32830423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202009226
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