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Murine Calprotectin Coordinates Mn(II) at a Hexahistidine Site with Ca(II)-dependent Affinity

Manganese is an essential metal ion that bacterial pathogens need to acquire from the vertebrate host during infection. In the mammalian nutritional immunity strategy to combat bacterial infection, the host restricts bacterial access to Mn(II) by sequestering this metal nutrient using the protein ca...

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Detalhes bibliográficos
Publicado no:Inorg Chem
Main Authors: Hadley, Rose C., Gagnon, Derek M., Ozarowski, Andrew, Britt, R. David, Nolan, Elizabeth M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6803030/
https://ncbi.nlm.nih.gov/pubmed/31145609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.inorgchem.9b00763
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