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Biochemical and Spectroscopic Observation of Mn(II) Transfer Between Bacterial Mn(II) Transport Machinery and Calprotectin

Human calprotectin (CP, S100A8/S100A9 oligomer) is a metal-sequestering host-defense protein that prevents bacterial acquisition of Mn(II). In this work, we investigate Mn(II) competition between CP and two solute-binding proteins that Staphylococcus aureus and Streptococcus pneumoniae, Gram-positiv...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Hadley, Rose C., Gagnon, Derek M., Brophy, Megan Brunjes, Gu, Yu, Nakashige, Toshiki G., Britt, R. David, Nolan, Elizabeth M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5762273/
https://ncbi.nlm.nih.gov/pubmed/29211955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b11207
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