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Computational Design of Affinity and Specificity at Protein-Protein Interfaces

The computer-based design of protein-protein interactions is a rigorous test of our understanding of molecular recognition and an attractive approach for creating novel tools for cell and molecular research. Considerable attention has been placed on redesigning the affinity and specificity of natura...

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Autors principals: Karanicolas, John, Kuhlman, Brian
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2882636/
https://ncbi.nlm.nih.gov/pubmed/19646858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2009.07.005
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