α-Conotoxin AuIB Isomers Exhibit Distinct Inhibitory Mechanisms and Differential Sensitivity to Stoichiometry of α3β4 Nicotinic Acetylcholine Receptors

Non-native disulfide isomers of α-conotoxins are generally inactive although some unexpectedly demonstrate comparable or enhanced bioactivity. The actions of “globular” and “ribbon” isomers of α-conotoxin AuIB have been characterized on α3β4 nicotinic acetylcholine receptors (nAChRs) heterologously...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Grishin, Anton A., Wang, Ching-I A., Muttenthaler, Markus, Alewood, Paul F., Lewis, Richard J., Adams, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Neurobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903359/
https://ncbi.nlm.nih.gov/pubmed/20466726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.111880
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados