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Identifying Key Amino Acid Residues That Affect α-Conotoxin AuIB Inhibition of α3β4 Nicotinic Acetylcholine Receptors
α-Conotoxin AuIB is a selective α3β4 nicotinic acetylcholine receptor (nAChR) subtype inhibitor. Its analgesic properties are believed to result from it activating GABA(B) receptors and subsequently inhibiting Ca(V)2.2 voltage-gated calcium channels. The structural determinants that mediate divergin...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
American Society for Biochemistry and Molecular Biology
2013
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3843058/ https://ncbi.nlm.nih.gov/pubmed/24100032 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.512582 |
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