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Structural mechanisms for α-conotoxin activity at the human α3β4 nicotinic acetylcholine receptor
Nicotinic acetylcholine receptors (nAChR) are therapeutic targets for a range of human diseases. α-Conotoxins are naturally occurring peptide antagonists of nAChRs that have been used as pharmacological probes and investigated as drug leads for nAChR related disorders. However, α-conotoxin interacti...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5374441/ https://ncbi.nlm.nih.gov/pubmed/28361878 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep45466 |
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