System x(c)(−) and Thioredoxin Reductase 1 Cooperatively Rescue Glutathione Deficiency

GSH is the major antioxidant and detoxifier of xenobiotics in mammalian cells. A strong decrease of intracellular GSH has been frequently linked to pathological conditions like ischemia/reperfusion injury and degenerative diseases including diabetes, atherosclerosis, and neurodegeneration. Although...

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Xehetasun bibliografikoak
Egile Nagusiak: Mandal, Pankaj Kumar, Seiler, Alexander, Perisic, Tamara, Kölle, Pirkko, Banjac Canak, Ana, Förster, Heidi, Weiss, Norbert, Kremmer, Elisabeth, Lieberman, Michael W., Bannai, Shiro, Kuhlencordt, Peter, Sato, Hideyo, Bornkamm, Georg W., Conrad, Marcus
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2010
Gaiak:
Metabolism
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903358/
https://ncbi.nlm.nih.gov/pubmed/20463017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.121327
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