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The Thioredoxin-Thioredoxin Reductase System Can Function in Vivo as an Alternative System to Reduce Oxidized Glutathione in Saccharomyces cerevisiae

Cellular mechanisms that maintain redox homeostasis are crucial, providing buffering against oxidative stress. Glutathione, the most abundant low molecular weight thiol, is considered the major cellular redox buffer in most cells. To better understand how cells maintain glutathione redox homeostasis...

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Main Authors: Tan, Shi-Xiong, Greetham, Darren, Raeth, Sebastian, Grant, Chris M., Dawes, Ian W., Perrone, Gabriel G.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825406/
https://ncbi.nlm.nih.gov/pubmed/19951944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.062844
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