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Thioredoxins function as deglutathionylase enzymes in the yeast Saccharomyces cerevisiae

BACKGROUND: Protein-SH groups are amongst the most easily oxidized residues in proteins, but irreversible oxidation can be prevented by protein glutathionylation, in which protein-SH groups form mixed disulphides with glutathione. Glutaredoxins and thioredoxins are key oxidoreductases which have bee...

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Detalhes bibliográficos
Main Authors: Greetham, Darren, Vickerstaff, Jill, Shenton, Daniel, Perrone, Gabriel G, Dawes, Ian W, Grant, Chris M
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836980/
https://ncbi.nlm.nih.gov/pubmed/20074363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2091-11-3
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