Generation of Infectious Feline Immunodeficiency Virus (FIV) Encoding FIV/Human Immunodeficiency Virus Chimeric Protease

Feline immunodeficiency virus (FIV) and human immunodeficiency virus type 1 (HIV-1) proteases (PRs) share only 23% amino acid identity and exhibit distinct specificities yet have very similar 3-dimensional structures. Chimeric PRs in which HIV residues were substituted in structurally equivalent pos...

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Hlavní autoři: Lin, Ying-Chuan, Torbett, Bruce E., Elder, John H.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2010
Témata:
Vaccines and Antiviral Agents
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903298/
https://ncbi.nlm.nih.gov/pubmed/20410281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00294-10
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