Alteration of Substrate and Inhibitor Specificity of Feline Immunodeficiency Virus Protease

Feline immunodeficiency virus (FIV) protease is structurally very similar to human immunodeficiency virus (HIV) protease but exhibits distinct substrate and inhibitor specificities. We performed mutagenesis of subsite residues of FIV protease in order to define interactions that dictate this specifi...

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Detalhes bibliográficos
Main Authors: Lin, Ying-Chuan, Beck, Zachary, Lee, Taekyu, Le, Van-Duc, Morris, Garrett M., Olson, Arthur J., Wong, Chi-Huey, Elder, John H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC111993/
https://ncbi.nlm.nih.gov/pubmed/10775609
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