Alteration of Substrate and Inhibitor Specificity of Feline Immunodeficiency Virus Protease

Feline immunodeficiency virus (FIV) protease is structurally very similar to human immunodeficiency virus (HIV) protease but exhibits distinct substrate and inhibitor specificities. We performed mutagenesis of subsite residues of FIV protease in order to define interactions that dictate this specifi...

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Bibliografische Detailangaben

Veröffentlicht in:	J Virol
Hauptverfasser:	Lin, Ying-Chuan, Beck, Zachary, Lee, Taekyu, Le, Van-Duc, Morris, Garrett M., Olson, Arthur J., Wong, Chi-Huey, Elder, John H.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2000
Schlagworte:	Vaccines and Antiviral Agents
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC111993/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10775609/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.10.4710-4720.2000
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