Streamlined syntheses of (−)-dictyostatin, 25,26-dihydro-16-desmethyldictyostatin, and 6-epi-25,26-dihydro-16-desmethyldictyostatin

The dictyostatins are a promising class of potential anticancer drugs because they are powerful microtubule stabilizing agents, but the complexity of their chemical structures is a severe impediment to their further development. Based on both synthetic and medicinal chemistry analyses, 25,26-dihydro...

Full description

Saved in:
Bibliographic Details
Main Authors: Zhu, Wei, Jiménez, María, Jung, Won-Hyuk, Camarco, Daniel P., Balachandran, Raghavan, Vogt, Andreas, Day, Billy W., Curran, Dennis P.
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903049/
https://ncbi.nlm.nih.gov/pubmed/20545347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja103537u
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items