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Triptolide reduces cyst formation in a neonatal to adult transition Pkd1 model of ADPKD
Background. Autosomal dominant polycystic kidney disease (ADPKD), a major cause of end-stage renal failure, results from genetic mutation of either polycystin-1 (Pkd1) or polycystin-2 (Pkd2). In order to develop novel therapies to treat the advancement of disease progression, numerous rodent models...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2902895/ https://ncbi.nlm.nih.gov/pubmed/20139063 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ndt/gfp777 |
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