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Triptolide reduces cyst formation in a neonatal to adult transition Pkd1 model of ADPKD

Background. Autosomal dominant polycystic kidney disease (ADPKD), a major cause of end-stage renal failure, results from genetic mutation of either polycystin-1 (Pkd1) or polycystin-2 (Pkd2). In order to develop novel therapies to treat the advancement of disease progression, numerous rodent models...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Leuenroth, Stephanie J., Bencivenga, Natasha, Chahboune, Halima, Hyder, Fahmeed, Crews, Craig M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2902895/
https://ncbi.nlm.nih.gov/pubmed/20139063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ndt/gfp777
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