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Triptolide Reduces Cystogenesis in a Model of ADPKD

Mutations in PKD1 result in autosomal dominant polycystic kidney disease, which is characterized by increased proliferation of tubule cells leading to cyst initiation and subsequent expansion. Given the cell proliferation associated with cyst growth, an attractive therapeutic strategy has been to ta...

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Detalhes bibliográficos
Main Authors: Leuenroth, Stephanie J., Bencivenga, Natasha, Igarashi, Peter, Somlo, Stefan, Crews, Craig M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2518446/
https://ncbi.nlm.nih.gov/pubmed/18650476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2008030259
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