Triptolide Reduces Cystogenesis in a Model of ADPKD

Mutations in PKD1 result in autosomal dominant polycystic kidney disease, which is characterized by increased proliferation of tubule cells leading to cyst initiation and subsequent expansion. Given the cell proliferation associated with cyst growth, an attractive therapeutic strategy has been to ta...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Leuenroth, Stephanie J., Bencivenga, Natasha, Igarashi, Peter, Somlo, Stefan, Crews, Craig M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society of Nephrology 2008
Pynciau:
Brief Communication
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2518446/
https://ncbi.nlm.nih.gov/pubmed/18650476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2008030259
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