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Triptolide Reduces Cystogenesis in a Model of ADPKD
Mutations in PKD1 result in autosomal dominant polycystic kidney disease, which is characterized by increased proliferation of tubule cells leading to cyst initiation and subsequent expansion. Given the cell proliferation associated with cyst growth, an attractive therapeutic strategy has been to ta...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society of Nephrology
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2518446/ https://ncbi.nlm.nih.gov/pubmed/18650476 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2008030259 |
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