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Triptolide Induced Transcriptional Arrest is Associated with Changes in Nuclear Sub-Structure

Triptolide, an active component of the medicinal herb, lei gong teng, is a potent anti-cancer and anti-inflammatory therapeutic. It potently inhibits NFκB transcriptional activation subsequent to DNA binding, although a precise mechanism is as yet unknown. Here, we report that triptolide also induce...

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Bibliografiske detaljer
Main Authors: Leuenroth, Stephanie J., Crews, Craig M.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2587069/
https://ncbi.nlm.nih.gov/pubmed/18593926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-6207
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