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The ADPKD genes pkd1a/b and pkd2 regulate extracellular matrix formation
Mutations in polycystin1 (PKD1) account for the majority of autosomal dominant polycystic kidney disease (ADPKD). PKD1 mutations are also associated with vascular aneurysm and abdominal wall hernia, suggesting a role for polycystin1 in extracellular matrix (ECM) integrity. In zebrafish, combined kno...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists Limited
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2860853/ https://ncbi.nlm.nih.gov/pubmed/20335443 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.003194 |
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