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An Improved Method for Generating Consistent Soluble Amyloid-beta Oligomer Preparations for In Vitro Neurotoxicity Studies

Soluble Aβ oligomers are recognized as playing a key role in Alzheimer’s disease (AD) pathophysiology. Despite their significance, many investigators encounter difficulty generating reliable preparations for in vitro and in vivo experiments. Solutions of Aβ are often unstable and soluble conformer p...

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Hlavní autoři: Ryan, Deborah A., Narrow, Wade C., Federoff, Howard J., Bowers, William J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2902796/
https://ncbi.nlm.nih.gov/pubmed/20452375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneumeth.2010.05.001
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