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An Alzheimer’s Disease-relevant Presenilin-1 Mutation Augments Amyloid-beta-induced Oligodendrocyte Dysfunction
White matter pathology has been documented in the brains of familial Alzheimer’s disease (FAD)-afflicted individuals during pre-symptomatic and pre-clinical stages of AD. How these defects in myelination integrity arise and what roles they may play in AD pathophysiology have yet to be fully elucidat...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3045399/ https://ncbi.nlm.nih.gov/pubmed/21294162 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.21131 |
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