Early Oligodendrocyte/Myelin Pathology in Alzheimer’s Disease Mice Constitutes a Novel Therapeutic Target

The detection of myelin disruptions in Alzheimer’s disease (AD)–affected brain raises the possibility that oligodendrocytes undergo pathophysiological assault over the protracted course of this neurodegenerative disease. Oligodendrocyte compromise arising from direct toxic effects imparted by pathol...

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Detalhes bibliográficos
Main Authors: Desai, Maya K., Mastrangelo, Michael A., Ryan, Deborah A., Sudol, Kelly L., Narrow, Wade C., Bowers, William J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2010
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928974/
https://ncbi.nlm.nih.gov/pubmed/20696774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.100087
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