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Triple-transgenic Alzheimer's disease mice exhibit region-specific abnormalities in brain myelination patterns prior to appearance of amyloid and tau pathology

Alzheimer's disease (AD) is a progressively debilitating brain disorder pathologically defined by extracellular amyloid plaques, intraneuronal neurofibrillary tangles, and synaptic disintegrity. AD has not been widely considered a disease of white matter, but more recent evidence suggests the e...

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Bibliografische gegevens
Hoofdauteurs: Desai, Maya K., Sudol, Kelly L., Janelsins, Michelle C., Mastrangelo, Michael A., Frazer, Maria E., Bowers, William J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2009
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2584762/
https://ncbi.nlm.nih.gov/pubmed/18661556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.20734
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