Presenilin-1 is associated with Alzheimer's disease amyloid.

Mutations in presenilin (PS)-1 and -2, located on chromosome 14 and 1 respectively, are the major association with early-onset familial Alzheimer's disease (FAD). FAD has also been linked to mutations in the amyloid beta precursor protein (beta PP), and the presence of the apolipoprotein E4 all...

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Autores principales: Wisniewski, T., Dowjat, W. K., Permanne, B., Palha, J., Kumar, A., Gallo, G., Frangione, B.
Formato: Artigo
Lenguaje:Inglês
Publicado: 1997
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1858010/
https://ncbi.nlm.nih.gov/pubmed/9250173
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