Size-dependent neurotoxicity of β-amyloid oligomers

The link between the size of soluble amyloid β (Aβ) oligomers and their toxicity to rat cerebellar granule cells (CGC) was investigated. Variation in conditions during in vitro oligomerization of Aβ(1-42) resulted in peptide assemblies with different particle size as measured by atomic force microsc...

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Main Authors: Cizas, Paulius, Budvytyte, Rima, Morkuniene, Ramune, Moldovan, Radu, Broccio, Matteo, Lösche, Mathias, Niaura, Gediminas, Valincius, Gintaras, Borutaite, Vilmante
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853175/
https://ncbi.nlm.nih.gov/pubmed/20153288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2010.02.001
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