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The Sulfated Triphenyl Methane Derivative Acid Fuchsin is a Potent Inhibitor of Amyloid Formation by Human Islet Amyloid Polypeptide and Protects Against the Toxic Effects of Amyloid Formation

Islet amyloid polypeptide (IAPP), also known as amylin, is responsible for amyloid formation in type 2 diabetes. The formation of islet amyloid is believed to contribute to the pathology of the disease by killing β-cells and it may also contribute to islet transplant failure. The design of inhibitor...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Meng, Fanling, Abedini, Andisheh, Plesner, Annette, Middleton, Chris T, Potter, Kathryn J., Zanni, Martin T, Verchere, C. Bruce, Raleigh, Daniel P.
التنسيق: Artigo
اللغة:Inglês
منشور في: 2010
الموضوعات:
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC2902639/
https://ncbi.nlm.nih.gov/pubmed/20452363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.05.001
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