Histone Deacetylase 3 Depletion in Osteo/Chondroprogenitor Cells Decreases Bone Density and Increases Marrow Fat

Histone deacetylase (Hdac)3 is a nuclear enzyme that contributes to epigenetic programming and is required for embryonic development. To determine the role of Hdac3 in bone formation, we crossed mice harboring loxP sites around exon 7 of Hdac3 with mice expressing Cre recombinase under the control o...

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Autori principali: Razidlo, David F., Whitney, Tiffany J., Casper, Michelle E., McGee-Lawrence, Meghan E., Stensgard, Bridget A., Li, Xiaodong, Secreto, Frank J., Knutson, Sarah K., Hiebert, Scott W., Westendorf, Jennifer J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2010
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2901996/
https://ncbi.nlm.nih.gov/pubmed/20628553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011492
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