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Insights into migraine mechanisms and Ca(V)2.1 calcium channel function from mouse models of familial hemiplegic migraine

Migraine is a very common disabling brain disorder with unclear pathogenesis. A subtype of migraine with aura (familial hemiplegic migraine type 1: FHM1) is caused by mutations in Ca(V)2.1 (P/Q-type) Ca(2+) channels. This review describes the functional consequences of FHM1 mutations in knockin mous...

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Detalhes bibliográficos
Autor principal: Pietrobon, Daniela
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2901975/
https://ncbi.nlm.nih.gov/pubmed/20194127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2010.188003
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