Functional Consequences of Mutations in the Human α(1A) Calcium Channel Subunit Linked to Familial Hemiplegic Migraine

Mutations in α(1A), the pore-forming subunit of P/Q-type calcium channels, are linked to several human diseases, including familial hemiplegic migraine (FHM). We introduced the four missense mutations linked to FHM into human α(1A-2)subunits and investigated their functional consequences after expre...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Hans, Michael, Luvisetto, Siro, Williams, Mark E., Spagnolo, Michele, Urrutia, A., Tottene, Angelita, Brust, Paul F., Johnson, Edwin C., Harpold, Michael M., Stauderman, Kenneth A., Pietrobon, Daniela
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1999
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6782159/
https://ncbi.nlm.nih.gov/pubmed/10024348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.19-05-01610.1999
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