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Familial hemiplegic migraine mutations increase Ca(2+) influx through single human Ca(V)2.1 channels and decrease maximal Ca(V)2.1 current density in neurons
Insights into the pathogenesis of migraine with aura may be gained from a study of human Ca(V)2.1 channels containing mutations linked to familial hemiplegic migraine (FHM). Here, we extend the previous single-channel analysis to human Ca(V)2.1 channels containing mutation V1457L. This mutation incr...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The National Academy of Sciences
2002
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC130625/ https://ncbi.nlm.nih.gov/pubmed/12235360 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.192242399 |
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