THE ROLE OF CHLORIDE ANION AND CFTR IN KILLING OF PSEUDOMONAS AERUGINOSA BY NORMAL AND CF NEUTROPHILS

Chloride anion is essential for myeloperoxidase to produce hypochlorous acid (HOCl) in neutrophils (PMNs). To define whether chloride availability to PMNs affects their HOCl production and microbicidal capacity, we examined how extracellular chloride concentration affects killing of Pseudomonas aeru...

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Autori principali: Painter, Richard G., Bonvillain, Ryan W., Valentine, Vincent G, Lombard, Gisele A., LaPlace, Stephanie G., Nauseef, William M., Wang, Guoshun
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2901559/
https://ncbi.nlm.nih.gov/pubmed/18353929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0907658
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